SilMA-001-Silk Fibroin Methacrylated

Description

Product introduction

Silk fibroin ( SF ) is derived from the degumming of silk, and is a polypeptide composed of a variety of amino acids. SF molecule includes a hydrophobic peptide chain ( H chain ) and a hydrophilic peptide chain ( L chain ). The special amino acid sequences of H chain and L chain make it form a variety of protein secondary conformations. The properties of silk fibroin materials can be effectively controlled by regulating the secondary structure of silk fibroin, including the preparation of high strength and high orientation materials. SF has good biocompatibility, biodegradability and high tensile strength. It has been used in various biomedical fields, including wound dressings, artificial blood vessels, cell culture, etc.

Silk fibroin methacryloyl ( SilMA ) is modified by methacryloyl modification of SF by glycidyl methacrylate to introduce double bonds on SF molecules. Due to the special spatial structure of SF molecule, it is easy to form crystallization and insoluble in water before modification. After the introduction of additional chemical groups, it can be quickly dissolved in water, which enables SilMA to be photocurable into hydrogels.

Storage

Dry kit: room temperature, 3 months; 4℃, 12 months; -20℃, 18 months. It is best to prepare it when using it.

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